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Regulation of Gene Expression ?
http://web.wi.mit.edu/young/pub/regulation.html
Overview of different aspects of gene expression, including transcription, chromatin modification, and analysis of whole genomes, from Massachusetts Institute of Technology, Cambridge, Mass, USA.
Eukaryotic Gene Expression Problem Set ?
http://www.biology.arizona.edu/molecular_bio/problem_sets/mol_genetics_of_eukaryotes/eukaryotes....
Multiple choice questions about post-transcriptional modification of RNA, promoters, and nuclear RNA processing. From: University of Arizona, USA 1997.
Ribosomes ?
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/Ribosomes.html
Explanation of how the information encoded in mRNA is translated into a polypeptide. Includes differences between prokaryotes and eukaryotes by John W. Kimball, now retired from Harvard College.
Role of the Ribosome ?
http://cellbio.utmb.edu/cellbio/ribosome.htm
Illustrated explanation of the ribosomal protein synthesis by Gwen V. Childs, University of Texas, Galveston, TX.
Molecular Genetics Webtext ?
http://opbs.okstate.edu/~melcher/MG/FMG01.html
An online textbook on chromosomes, principles of genetic engineering, basic molecular genetics and experimental methods.
Genomes to Life ?
http://doegenomestolife.org/
The US Department of Energy at Oak Ridge program for research in moleular biology: goals and results.
Mammary Genome Anatomy Project ?
http://mammary.nih.gov/
Forum to integrate various aspects of mammary gland biology, including cellular and developmental aspects, and to promote collaborations and the exchange of ideas, knowledge and resources at NIH, Maryland.
Biochemistry of Nucleic Acids ?
http://oregonstate.edu/instruction/bb492/general/schedule.html
Lecture notes on nucleic acid structure, DNA replication and repair, the genetic code and translation, as well as cancer genes, from Oregon State University, USA 2003.
Alternative Splicing ?
http://www.exonhit.com/alternativesplicing/
Resource for intervention in the key steps in post-translocation regulatory process, with analysis tools and implications in pathologies. Maintained by Exonhit Therapeutics SA, Paris, France.
Gene Expression: Transcription ?
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/Transcription.html
Resource for transcription events during gene formation including schematic diagrams.
Genome-Wide Expression ?
http://web.wi.mit.edu/young/expression/home.html
Report on a project to analyze the transcriptional regulatory circuitry of the yeast cell. From the Young Lab at the Whitehead Institute for Biomedical Research.
Anatomy of a Comparative Gene Expression Study ?
http://www.cs.wustl.edu/~jbuhler/research/array/
Clear explanation of the process of comparing the gene expression in two cell populations or tissue samples by fluorescent microarray technique.
Serial Analysis of Gene Expression ?
http://www.sagenet.org/
Explanation of Serial Analysis of Gene Expression (SAGE), a method for analysis of gene expression patterns.
Gene Expression ?
http://en.wikipedia.org/wiki/Gene_expression
Article in Wikipedia.
3'UTR ?
http://en.wikipedia.org/wiki/3%27_UTR
Wikipedia article on the untranslated regions at the ends of mRNA.
Alternative Splicing ?
http://en.wikipedia.org/wiki/Alternative_splicing
Wikipedia article on the process in eukaryotes in which the splicing process of a pre-mRNA can lead to different ripe mRNA molecules and therefore to different proteins.
Enhancer ?
http://en.wikipedia.org/wiki/Enhancer
Wikipedia article on enhancers, short pieces of DNA which bind to trans-acting factors to enhance transcription levels of genes.
Epigenetics ?
http://en.wikipedia.org/wiki/Epigenetics
Wikipedia article on processes that lead to inheritance that is not reflected in the sequences of the nuclear DNA.
Exon ?
http://en.wikipedia.org/wiki/Exon
Wikipedia article on regions in genes that are expressed in mature mRNA and in proteins.
Intron ?
http://en.wikipedia.org/wiki/Intron
Wikipedia article on sections of genes that are eliminated by splicing in the formation of mature mRNA and therefore not expressed as proteins.
Expressed Sequence Tag ?
http://en.wikipedia.org/wiki/Expressed_sequence_tag
Wikipedia article: EST are short sub-sequences of genes, used in mRNA sequencing and in construction of DNA microarrays.
Gene Regulation ?
http://en.wikipedia.org/wiki/Gene_regulation
Wikipedia article on the mechanisms that regulate gene expression.
Gene Regulatory Network ?
http://en.wikipedia.org/wiki/Gene_regulatory_network
Wikipedia article on the mathematical modelling of gene expression as a network.
Genetic Code ?
http://en.wikipedia.org/wiki/Genetic_code
Wikipedia article on the relationship between the nucleic acid base sequence and the corresponding polypeptide amino acid sequence.
Imprinting ?
http://en.wikipedia.org/wiki/Imprinting_%28genetics%29
Wikipedia article on the suppressing of genes by chemical modification, depending on which parent they were received from.
Messenger RNA ?
http://en.wikipedia.org/wiki/Messenger_RNA
Wikipedia article on the RNA that carries information from DNA to protein synthesis.
Monocistronic ?
http://en.wikipedia.org/wiki/Monocistronic
Wikipedia article: Messenger RNA that codes for one polypeptide string only.
Noncoding DNA ?
http://en.wikipedia.org/wiki/Noncoding_DNA
Wikipedia article: sections of DNA that do not contain codes for polypeptide sequences.
Operon ?
http://en.wikipedia.org/wiki/Operon
Wikipedia article: group of genes in primitive organisms that are controlled by one operator and one promoter to be activated together.
Posttranslational modification ?
http://en.wikipedia.org/wiki/Posttranslational_modification
Wikipedia article: chemical modification of polypeptide chains after synthesis.
Pre-mRNA ?
http://en.wikipedia.org/wiki/Pre-mRNA
Wikipedia article: RNA string syntesized in the cell nucleus before modification (splicing, polyadenylation) and export to the cytoplasm.
Promoter ?
http://en.wikipedia.org/wiki/Promoter
Wikipedia article: in genetics a sequence located upstream of a gene that enables its translation.
Protein biosynthesis ?
http://en.wikipedia.org/wiki/Protein_biosynthesis
Wikipedia article: summary of the process by which the cell converts the DNA sequence proteins.
SECIS element ?
http://en.wikipedia.org/wiki/SECIS_element
Wikipedia article: Sequence that directs translation of UGA as selenocysteine insteado of using it as a stop codon.
Shine-Dalgarno sequence ?
http://en.wikipedia.org/wiki/Shine-Dalgarno_sequence
Wikipedia article: signals the initiation of protein synthesis in bacteria.
Signal peptide ?
http://en.wikipedia.org/wiki/Signal_peptide
Wikipedia article: short peptide sequences that direct the post-translational transport of proteins after synthesis.
Spliceosome ?
http://en.wikipedia.org/wiki/Spliceosome
Wikipedia article: particle composed of DNA and peptide chains that effects mRNA splicing in the cell nucleus of eucaryotic cells.
Splicing ?
http://en.wikipedia.org/wiki/Splicing_%28genetics%29
Wikipedia article: in genetics, the process of removing introns from mRNA in the cell nucleus before export to the cytoplasm and use as master for protein synthesis.
Transcription ?
http://en.wikipedia.org/wiki/Transcription_%28genetics%29
Wikipedia article: in genetics the process by which a DNA sequence is converted to a corresponding RNA sequence.
Translation ?
http://en.wikipedia.org/wiki/Translation_%28genetics%29
Wikipedia article: in genetics, the process by which ribosomes in the cytoplasm transfer the genetic code from a m-RNA sequence to an amino acid sequence in a polypeptide chain.
Transcription Factor ?
http://en.wikipedia.org/wiki/Transcription_factor
Proteins that specifically bind to promotor or enhancer regions on DNA and thereby control the transcription of the downstream gene.
Transfer RNA ?
http://en.wikipedia.org/wiki/Transfer_RNA
Wikipedia article: small RNA molecules that transport amino acids to their positions on the ribosome during polypeptide synthesis.
Gene Expression ?
http://www.gnxp.com
Independent forum for discussion of gene expression.
Epigenetic inheritance ?
http://en.wikipedia.org/wiki/Epigenetic_inheritance
Transmission of information from a cell or multicellular organism to its descendants without that information being encoded in the nucleotide sequence of the gene. Wikipedia article.
European Sequencing of Tobacco ?
http://www.estobacco.info
A collaboration between Advanced Technologies (Cambridge) Ltd and Tobacco Institute of Bergerac to sequence a large number of tobacco genes.
The Epigenome Network of Excellence ?
http://www.epigenome-noe.net/
Network of research groups on heritable changes in gene expression without a change in DNA sequence, funded by the European Union.
Epigenetics ?
http://www.cellcentric.co.uk/epigenetics.htm
Article on the site of CellCentric on epigenetics.
Epigenetic Station ?
http://www.epigeneticstation.com
With information, protocols and resources about epigenetics and DNA methylation and much advertising.
Laboratory of Intelligent Systems ?
http://lis.epfl.ch
Project at the Ecole Polytechnique Fédérale de Lausanne (EPFL) creating electronic models of the evolution of gene expression, neural development and similar evolution processes.
Control of Gene Expression ?
http://www.accessexcellence.org/RC/VL/GG/ecb/gene_expression.html
A collection of diagrams illustrating the fundamentals of molecular biology.
RiboWeb Project ?
http://helix-web.stanford.edu/ribo3dmodels/index.html
Knowledge base that combines data on the structure of the prokaryotic 30S ribosomal subunit that initiates the translation of mRNA into protein, its function and related links and references.
6th International Summer School "Biocomplexity from System to Gene" ?
http://www.fulton.asu.edu/%7ebioc2007/
Summaries and reports from a summer school in Istambul, Turkey July 2007.
Epigenetics Research ?
http://www.epidna.com
News, jobs, recent literature, lab registry and an ontologically driven database that is updated daily.
Reportergene ?
http://reportergene.blogspot.com/
Information and news related to reporter genes, that are used to monitor activation of genes and groups of genes that are otherwise difficult to follow.

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